آدرس مطب
Exploring the potential of myo-inositol in thyroid disease management-focus on thyroid cancer diagnosis and therapy
Authors S Adeleh Razavi, Mohadeseh Kalari, Tahereh Haghzad, Fatemeh Haddadi, Shirzad Nasiri, Mehdi Hedayati Publication date 2024/9/12 [...]
The role of methylation quantification of circulating tumor DNA (ctDNA) as a diagnostic biomarker of Pheochromocytomas (PCCs) and Paragangliomas (PGLs)
Authors Fatemeh Khatami, Leonardo Oliveira Reis, Mehdi Ebrahimi, Shirzad Nasiri, Seyed Mohammad Tavangar, Mahin Ahmadi Pishkuhi, Gita Shafiee, Ramin Heshmat, Seyed Mohammad Kazem Aghamir Publication date 2024/7/20 [...]
Applying Translaryngeal Ultrasonography in Unilateral Vocal Cord Paralysis before Thyroid Cancer Reoperation- A Single Center Study
Authors Sam Moslemi, Shirzad Nasiri, Sina Sharghi, Aidin Yaghoubi Notash Publication date 2024/6/30 [...]
Comparison of endoscopic versus focused parathyroidectomy in surgical management of single-gland primary hyperparathyroidism-a randomized clinical trial
Authors Seyed Mostafa Meshkati Yazd, Reza Shahriarirad, Sara Nayebi, Paniz Dehghan, Amirbahador Abbasi, Farhood Maghsoodloo, Kaveh Hamedani, Shirzad Nasiri Publication date 2024/6/22 [...]
Elevated Plasma Levels of MT4-MMP and MT6-MMP; A New Observation in Patients with Thyroid Nodules
Authors Khadijeh Shirazkeytabar, S Adeleh Razavi, Raziyeh Abooshahab, Pouya Salehipour, Mahdi Akbarzadeh, Ahmadreza Soroush, Mehdi Hedayati, Shirzad Nasiri Publication date 2023/6 [...]
Investigating the effectiveness of intraoperative rapid parathyroid hormone assay in parathyroidectomy surgery in patients with secondary hyperparathyroidism
Authors Shirzad Nasiri, Seyed Mostafa Meshkati Yazd, Alireza Heshmati, Abnoos Mokhtari Ardekani, Masoud Najafi, Reza Shahriarirad Publication date 2023/5/25 [...]
Calcitriol supplementation before parathyroidectomy and calcium level after surgery in parathyroid adenoma patients: a randomized controlled trial
Authors R Shahriarirad, SM Meshkati Yazd, A Ardekani, A Mokhtari Ardekani, N Moradi, S Nasiri Publication date 2023/5 [...]
Circulating Tumor DNA (ctDNA) Methylation Quantification As Diagnostic Biomarker of Pheochromocytomas (PCCs) and Paragangliomas (PGLs)
Authors Fatemeh Khatami, Leonardo Oliveira Reis, Mehdi Ebrahimi, Shirzad Nasiri, Seyed Mohammad Tavangar, Mahin Ahmadi Pishkuhi, Gita Shafiei, Ramin Heshmat, Seyed Mohammad Kazem Aghamir Publication date 2023/4/17 [...]
Evaluation of the role of prophylactic bilateral central neck lymph node dissection in patients with papillary thyroid carcinoma: a case controlled study
Authors Reza Shahriarirad, Seyed Mostafa Meshkati Yazd, Roya Zahedi, Abnoos Mokhtari Ardekani, Mohammad Mustafa Rekabi, Shirzad Nasiri Publication date 2023/4 [...]
Plasma metabolites analysis of patients with papillary thyroid cancer- A preliminary untargeted 1H NMR-based metabolomics
Publication date 2024/4/15 Metabolomics plays a crucial role in identifying molecular biomarkers that can differentiate pathological conditions. [...]
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The evaluation of locoregional tumoral involvement in the cooccurrence of hashimoto thyroiditis with papillary thyroid cancer-a case controlled study
Authors Shirzad Nasiri, Seyed Mostafa Meshkati Yazd, Mahsa Gholami, Sepehr Shahriarirad, Sina Sharghi, Reza Shahriarirad Publication date 2023/12 [...]
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The effect of thymectomy during central neck dissection in papillary thyroid carcinoma-a case-controlled study
Authors Shirzad Nasiri, Seyed Mostafa Meshkati Yazd, Abnoos Mokhtari Ardekani, Andarz Fazlollahpour-Naghibi, Mona Shahintaj, Reza Shahriarirad Publication date 2023/1 [...]
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Evaluation of the role of prophylactic bilateral central neck lymph node dissection in patients with papillary thyroid carcinoma-a case controlled study
Authors Reza Shahriarirad, Seyed Mostafa Meshkati Yazd, Roya Zahedi, Abnoos Mokhtari Ardekani, Mohammad Mustafa Rekabi, Shirzad Nasiri [...]
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Calcitriol supplementation before parathyroidectomy and calcium level after surgery in parathyroid adenoma patients-a randomized controlled trial
Authors R Shahriarirad, SM Meshkati Yazd, A Ardekani, A Mokhtari Ardekani, N Moradi, S Nasiri Publication date 2022/12/2 [...]
Autotransplantation of parathyroid tissue into subcutaneous subclavicular area following total parathyroidectomy in secondary hyperparathyroidism
S Nasiri, SM Meshkati Yazd, H Kamran, MS Kahrizi, M Azhdari, R Shahriarirad Publication date 2022/12 [...]
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Hypermethylated RASSF1 and SLC5A8 promoters alongside BRAFV600E mutation as biomarkers for papillary thyroid carcinoma
Fatemeh Khatami, Bagher Larijani, Ramin Heshmat, Shirzad Nasiri, Mohammad Haddadi‐Aghdam, Ladan Teimoori‐Toolabi, Seyed M Tavangar Publication date 2020/10 [...]
Instructional Self-Talk on Motor Learning in Children with Attention-Deficit Hyperactivity Disorder
A Bakhtiari, A Hashemi, S Nasiri Publication date 2020/1/1 [...]
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Relationship between preoperative 25-hydroxy vitamin D and surgical site infection
Ali Ghorbani Abdehgah, Amir Monshizadeh, Mohammadreza Mohajeri Tehrani, Shirin Afhami, Behnam Molavi, Mahdi Jafari, Shirzad Nasiri, Ahmadreza Soroush Publication date 2020/1/1 [...]
Validation of reference genes for normalization of relative qRT-PCR studies in papillary thyroid carcinoma
S Adeleh Razavi, Mandana Afsharpad, Mohammad Hossein Modarressi, Maryam Zarkesh, Parichehreh Yaghmaei, Shirzad Nasiri, S Mohammad Tavangar, Hanieh Gholami, Afsoon Daneshafrooz, Mehdi Hedayati Publication date 2019/10/23 [...]
Circulating ctDNA methylation quantification of two DNA methyl transferases in papillary thyroid carcinoma
Fatemeh Khatami, Ladan Teimoori‐Toolabi, Ramin Heshmat, Shirzad Nasiri, Hiva Saffar, Mahsa Mohammadamoli, Mohammad Haddadi Aghdam, Bagher Larijani, Seyed Mohammad Tavangar Publication date 2019/10 [...]
-Hsa-miR-942 fingerprint in colorectal cancer through Wnt signaling pathway
Ali Fasihi, Bahram M Soltani, Zahra Sadat Ranjbaran, Sajedeh Bahonar, Romina Norouzi, Shirzad Nasiri Publication date 2019/9/5 [...]
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Promoter methylation of four tumor suppressor genes in human papillary thyroid carcinoma
Fatemeh Khatami, Bagher Larijani, Ramin Heshmat, Shirzad Nasiri, Hiva Saffar, Gita Shafiee, Azam Mossafa, Seyed Mohammad Tavangar Publication date 2019 [...]
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Liquid biopsy as a minimally invasive source of thyroid cancer genetic and epigenetic alterations
Fatemeh Khatami, Bagher Larijani, Shirzad Nasiri, Seyed Mohammad Tavangar Publication date 2019 [...]
Introduction of hsa‐miR‐103a and hsa‐miR‐1827 and hsa‐miR‐137 as new regulators of Wnt signaling pathway and their relation to colorectal carcinoma
Ali Fasihi, Bahram M. Soltani, Amir Atashi, Shirzad Nasiri Publication date 2018/7 [...]
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Comparison of surgical site infections between laparoscopic and open cholecystectomy
Shervin Asgari, Pegah Mohaghegh, Ali Ghorbani-Abdehgah, Behnam Molavi, Aidin Yaghoobi-Notash, Ali Mir, Reza Saeedi, Shirzad Nasiri, Reza Eslamian, Abolfazl Shojaiefard, Mehdi Jafari, Ahmadreza Soroush [...]
Clinical outcome of thymectomy in myasthenia gravis patients-A report from Iran
Benyamin Seyfari, Farzad Fatehi, Abolfazl Shojaiefard, Mehdi Jafari, Ali Ghorbani-Abdehgah, Shirzad Nasiri, Aidin Yaghoobi-Notash, Behnam Molavi, Amir Hossein Latif, Reza Eslamian, Ali Mir, Ahmadreza Soroush Publication date 2018/1/1 [...]
Pancreas Transplantation-A Review of Literature
Maria Ajdari, Reza Saidi, Mehdi Jafari, Abolfazl Shojaiefard, Shirzad Nasiri, Ali Mir, Ahmadreza Soroush Publication date 2017/12/29 [...]
The effect of ticlopidine on early arteriovenous fistula thrombosis-A randomized clinical trial
Behnam Molavi, Abolfazl Shojaiefard, Mehdi Jafari, Ali Ghorbani-Abdehgah, Shirzad Nasiri, Aidin Yaghoobi-Notash, Ali Mir, Ahmadreza Soroush 2017/7/25 [...]
Thyroid lymphoma arising from Hashimoto`s thyroiditis
Authors: Nasiri, S., Mahmoodzadeh, H., Sharifi, M.Journal : ANZ Journal of Surgery [...]
Prognostic factors in survival of colorectal cancer patients after surgery
Objective: To determine the factors affecting survival, following resection of large bowel for colorectal carcinoma. Method: From the cancer database of a single referral institution, a total of 1090 patients who had undergone colorectal resection between 1999 and 2002 were identified. Cases with recurrent colorectal cancer or previous history of neoadjuvant chemotherapy were excluded. Survival curves were plotted using the Kaplan-Meier method. Univariate analysis of factors thought to influence... [...]
Isolated primary hydatid disease of omentum; report of a case and review of the literature
Hydatid disease, most commonly caused by the larval stage of Echinococcus granulosus, affects mainly human liver and lung, and rarely other parts of the body. It is prevalent in most sheep-raising Mediterranean Countries including Iran. Perito- neal hydatid cyst, either primary or secondary, represents an uncommon but significant manifestation of the disease. The present case report describes a case of primary isolated hydatid disease of omentum, which to our knowledge constitutes the first case... [...]
Accuracy of serum pepsinogens I and II, gastrin-17 and anti-helicobacter pylori antibodies in histological diagnoses of atrophic gastritis
Aim. Atrophic gastritis is defined as a chronic inflammatory process in gastric mucosa leading to loss of glandular cells. It is considered a precancerous condition, thus its early diagnosis is of importance. Although histopathologic studies remain as the gold standard of diagnosis, non-invasive methods suitable for screening purposes are being developed. This includes measurement of serum gastric profile. Methods. Two hundred and fifty 250 patients who were planned to undergo upper gastrointestinal... [...]
Lack of cytomegalovirus and polyomavirus coexistence in iranian kidney transplant recipients
Introduction: Maintenance of kidney graft function is essential, averting infection and coinfection. Cytomegalovirus (CMV) and BK polyomavirus (BKV) coinfection have been reported. There are a few studies of CMV and BKV infection in kidney transplant recipients in Iran, but no studies of their coinfection. Objective: To assess the coexistence of CMV and BKV infection in renal transplant recipients. Patients and Methods: The presence of CMV and BKV was assessed using real-time polymerase chain reaction... [...]
Stent-and-glue sutureless vascular anastomosis
Vascular anastomosis is commonly done by hand-sewn methods which not only are slow in pace, but also need experiences in surgeons` hands. As the old techniques are replaced by the new ones all the time, it is sensed that a new sutureless approach should be welcomed in the field of vascular anastomosis. Although lots of efforts have been done, such previous recommended techniques are associated with adverse consequences and here is where the need for new methods is still sensed. In this manuscript,... [...]
Fine-needle aspiration cytology and flow cytometric immunophenotyping in diagnosis and classification of non-Hodgkin lymphoma in comparison to histopathology
This prospective study aimed to compare the value of fine needle aspiration (FNA) cytology (FNAC) and flow cytometric immunophenotyping (FCI) with histopatopathology (HP) in the diagnosis and classification of non-Hodgkin lymphoma (NHL). Twenty-nine excised lymph nodes suspected of NHL were evaluated using FNAC, FCI, and HP. Specimens were divided into two equal parts; one for HP and the other for FNAC and FCI. Results were compared in terms of diagnosis (malignant, benign or reactive, and metastatic)... [...]
Diagnostic values of ultrasound and the Modified Alvarado Scoring System in acute appendicitis
Background: Making the diagnosis of acute appendicitis is difficult, and is important for preventing perforation of the appendix and negative appendectomy results. Ultrasound and clinical scoring systems are very helpful in making the diagnosis. Ultrasound is non-invasive, available and cost-effective, and can accomplish more than CT scans. However, there is no certainty about its effect on the clinical outcomes of patients, and it is operator dependent. Counting the neutrophils as a parameter of... [...]
Randomized clinical trial of subcutaneous versus interfascial bupivacaine for pain control after midline laparotomy
Background Although patient-controlled analgesia for pain management after abdominal surgery is common, efforts to find alternative effective methods to control postoperative pain are continuing. The aim of this study was to compare postoperative pain levels following intermittent regional administration of bupivacaine via a catheter placed in the rectus sheath or subcutaneously at abdominal surgery through midline incisions. Methods Consecutive patients undergoing elective midline laparotomy were... [...]
Does corticosteroid have any beneficial effect on voice change after thyroidectomy
Voice alteration is one of the most common complications after thyroidectomy. It has a serious effect on social communication and economic and psychosocial status of patients. It has been hypothesized that inflammation and edema in the surgery site has a major role in voice change after thyroidectomy. This randomized clinical trial study was design to evaluate the effect of a single preoperative dose of steroid on voice change after thyroidectomy. This is a prospective randomized clinical trial with... [...]
A randomized clinical trial comparing 4-Port, 3-Port, and single-incision laparoscopic cholecystectomy
Backgrounds: Despite increasing trend in single incision laparoscopic cholecystectomy (SILC), there is still controversy regarding its global acceptance as a routine practice. Our study aimed to compare surgical events, early in-hospital and later outcomes of SILC with conventional multiport laparoscopic cholecystectomy (LC). Methods: Through a randomized controlled trial (RCT) between June and December 2011, 90 consecutive patients with documented biliary diseases waiting for LC were equally allocated... [...]
Risk factors for the development of complicated appendicitis in adults
Objective: To investigate the patient`s history and physical examination information to find out risk factors associated with complicated appendicitis. Material and Methods: Two hundred patients who were admitted with complicated appendicitis (including abscess, phlegmon, and generalized peritonitis) were retrieved from our database. Two hundred patients with non-complicated acute appendicitis were randomly selected from the same period. These two groups were compared in terms of demographic characteristi... [...]
Association of vitamin D levels and receptor gene polymorphisms with medullary thyroid cancer
Background: Thyroid cancer is the most common endocrine malignancy. Accounting for approximately 1-2% of all cancers. Thyroid cancers have been divided into four main types: papillary, follicular, medullary and anaplastic. The active form of vitamin D (1,25-(OH) 2-vitamin D3) by binding to its receptor, using genomic and nongenomic mechanisms inhibits the proliferative effect of TSH on thyroid cells. Therefore, vitamin D may have a role in regulating of thyroid gland cell proliferation. Many studies... [...]
Comparison the effect of stump closure by endoclips versus endoloop on the duration of surgery and complications in patients under laparoscopic appendectomy,A randomized clinical trial
Background: Laparoscopic appendectomy is a well‑described surgical technique. However, concerns still exist regarding whether the closure of the appendiceal stump should be done with a clip, an endoloop, or other techniques. In this study, the effect of stump closure on duration of surgery and complications by endoclips was compared with endoloop in patients under laparoscopic appendectomy. The study was carried out as a prospective randomized clinical trial between 2013 and 2015 in Shariati... [...]
A prospective double-blinded randomized controlled trial comparing systemic stress response in Laparoascopic cholecystectomy between low-pressure and standard-pressure pneumoperitoneum
Introduction: Laparoscopic cholecystectomy (LC) has become the gold-standard treatment for gallstone diseases. However, despite huge reduction in operative injury, systemic stress response remains high. This randomized controlled trial (RCT) aimed to compare systemic stress response between 2 different techniques of CO2 pneumoperitoneum. Methods: Trough a prospective, double-blinded RCT, serum levels of cortisol, adrenaline, glucose, and C-reactive protein (CRP) were compared between the two groups... [...]
Evaluation of platelet-rich plasma gel potential in acceleration of wound healing duration in patients underwent pilonidal sinus surgery: A randomized controlled parallel clinical trial
Objectives One of the most important surgical issues applied in the treatment of pilonidal sinus disease is wound healing. The aim of this study was to investigate the possible effect of platelet-rich plasma (PRP) gel on accelerating wound healing in these patients. Methods In this randomized, controlled, parallel group clinical trial, 110 patients were randomly allocated into two parallel groups with the same size (controls and treatment arm) after meeting inclusion and exclusion criteria. After... [...]
The effect of omentoplasty on the rate of anastomotic leakage after intestinal resection,A randomized controlled trial
Anastomotic leakage is a major postoperative complication after intestinal surgery leading to increased risk of morbidity and mortality. Omentoplasty has been evaluated to prevent anastomotic leakage in several studies. However, there is no consensus regarding whether or not omentoplasty should be used to decrease the rate of anastomotic leakage after intestinal resection. A prospective, randomized study was conducted to evaluate the influence of omentoplasty on anastomotic leakage after intestinal... [...]
Meta-analysis of promoter methylation in eight tumor-suppressor genes and its association with the risk of thyroid cancer
Promoter methylation in a number of tumor-suppressor genes (TSGs) can play crucial roles in the development of thyroid carcinogenesis. The focus of the current meta-analysis was to determine the impact of promoter methylation of eight selected candidate TSGs on thyroid cancer and to identify the most important molecules in this carcinogenesis pathway. A comprehensive search was performed using Pub Med, Scopus, and ISI Web of Knowledge databases, and eligible studies were included. The methodological... [...]
Alternative splicing of the OCC-1 gene generates three splice variants and a novel exonic microRNA, which regulate the Wnt signaling pathway
The Wnt signaling pathway is hyperactivated in most colorectal cancers (CRC). Finding new regulators of this pathway represents the potential for cancer diagnosis or treatment. OCC-1 was initially reported as an up-regulated gene in colon carcinoma, without knowing its mechanism of action. Here, two novel transcript variants and an exonic microRNA that originated from the OCC-1 gene are reported, showing positive effects on Wnt activity. Up-regulation of the known OCC-1 variant (assigned as OCC-1A/B)... [...]
A practical score model for detecting malignant thyroid nodules by using ultrasonographic findings
About 10% of thyroid nodule Fine Needle Aspirations (FNAs) are reported indeterminate, and this number is much higher in Iran. All of these patients undergo thyroid surgery, whereas, only about 20% of them are malignant and they did not need surgery. Therefore, we decided to evaluate the ultrasonographic features of malignant thyroid nodules to find a predictive scoring model for thyroid nodules and consequently reduce the unnecessary thyroid surgeries. This prospective cross-sectional study was... [...]
Introduction of hsa-miR-103a and hsa-miR-1827 and hsa-miR-137 as new regulators of Wnt signaling pathway and their relation to colorectal carcinoma
Wnt signaling is hyper-activated in most of human cancers including colorectal carcinoma (CRC). Therefore, the introduction of new regulators for Wnt pathway possesses promising diagnostic and therapeutic applications in cancer medicine. Bioinformatics analysis introduced hsa-miR-103a, hsa-miR-1827, and hsa-miR-137 as potential regulators of Wnt signaling pathway. Here, we intended to examine the effect of these human miRNAs on Wnt signaling pathway components, on the cell cycle progression in CRC... [...]
Hsa-miR-942 fingerprint in colorectal cancer through Wnt signaling pathway
Article has an altmetric score of 1 Altmetrics The Wnt signaling pathway has been identified for its function in carcinogenesis and embryonic development. It is known to play a vital role in the initiation and development of colorectal cancer (CRC). Therefore, it is of great importance for CRC research to illuminate the mechanisms which regulate Wnt pathway activity. Here, we intended to examine the effect of hsa-miR-942 (miR-942) on the Wnt signaling activity, cell cycle progression, and its expression in CRC tissues. RT-qPCR results indicated... [...]